Microinjection (ICSI)
Microinjection, a.k.a. ICSI, one of the fertilization methods used in IVF treatment, is a procedure performed in a laboratory setting. After being obtained, the eggs are processed using special procedures, and the most qualified and mature ones are separated. A micromanipulator device is used to inject sperm into each separated mature egg. The eggs, along with sperm, are kept in specially prepared solutions that resemble the mother’s uterus. This procedure is carried out in a device known as an incubator. The fertilization status of the eggs is assessed 16-18 hours after microinjection.
What Factors Influence Microinjection Method Success?
Not only is egg count and quality important in ICSI, but so is sperm count. There should be both healthy eggs and healthy sperm available. The sufficiency of the sperm count and the suitability of the ejaculate structure for fertilization boosts the success rate by up to In cases such as azoospermia, sperm can be obtained surgically, and microinjection can be used in this manner.
There is a strong relationship between success rate and egg maturity. To use microinjection, mature eggs must be present. The injected sperms’ ejaculate structure influences fertilization rate once more. As a result of the procedures, not all embryos will be of the same quality. As a result, when the egg and sperm counts are high, the success rate is higher.
When Is The Microinjection Applied?
Generally, microinjection is a method, which is preferred within the scope of man related infertility problems. It is applied for the individuals whose sperm count is low, who do not have sufficient sperm movement, have sperm deformities and whose fertilization rate is low in vitro fertilization (IVF) method which has been applied before. It is applied for the women, whose egg count is low when it comes to woman related causes.
What Are The Advantages Of Microinjection Method?
In vitro fertilization (IVF), which is among classical and conventional methods, is a backward method compared to today’s in vitro fertilization (IVF) technology. ICSI has a higher success rate compared to IVF. Generally, microinjection is a method, which is preferred within the scope of man related infertility problems. As a result, in cases of low sperm count, the success rate is higher.
Fertilization is expected to occur after the egg and sperm are placed in the same environment in IVF. In ICSI, the sperm is injected directly into the egg. This is one of the differences that significantly increases the success rate.