Advanced Age Pregnancy

What is Advanced Maturity?

The most common cause of infertility in women is advanced age.
As a woman ages, her egg reserve and quality begin to decrease, significantly reducing fertility rates.
A woman’s body is at its most reproductively fertile in her 20s.

• In their 20s: Pregnancy rate ≈ 25%
• After age 30: Pregnancy rate ≈ 20%
• After age 40: Pregnancy rate ≈ 5%

This is related to women aging and approaching menopause, and the natural changes that occur in hormone levels.

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Why does the chance of getting pregnant decrease with age?

1. Decrease in Egg Reserve

Women are born with a limited number of eggs.
As they age, ovarian reserve (AMH and follicle count) decreases.
This makes ovulation more difficult and reduces the likelihood of natural pregnancy.

2. Decrease in Egg Quality

Egg quality varies depending on the number of chromosomes
they contain. Abnormalities in chromosome number increase the risk of miscarriage.
Therefore, eggs fertilized at an older age tend to be genetically unhealthy.

3. Uterine and Hormonal Changes

With age, uterine tissue can thicken, blood flow can decrease, and hormonal balance can change. This reduces the chances of embryo implantation.

4. Risk of Genetic Diseases

The incidence of Down syndrome and similar chromosomal disorders increases with age.
Therefore, genetic screening (PGT) is of great importance in pregnancies at advanced ages.

How to Get Pregnant at an Older Age?

Although the chances of natural pregnancy decrease in older expectant mothers, successful results can be achieved thanks to modern in-vitro fertilization (IVF) treatments.

In Vitro Fertilization (IVF) Treatment

Eggs are collected, fertilized with sperm, and healthy embryos are transferred to the uterus. At older ages, genetic analysis is recommended to detect chromosomal abnormalities.

Preimplantation Genetic Diagnosis (PGT)

PGT allows for the examination of the chromosomal structure of embryos.
This ensures that only healthy embryos are transferred, reducing the risk of miscarriage.
PGT significantly increases the success rate in women over 38 years of age.

Egg Freezing (Planning at an Early Age)

Women who do not yet plan to become mothers but intend to conceive later in life can preserve their fertility by freezing their eggs at a young age.

Risks of Pregnancy at Advanced Age

Pregnancy at an advanced age carries certain risks for both the mother and the baby’s health:

These risks are not the same for every individual.
At FertiJin IVF Center, a personalized treatment plan is prepared by evaluating the prospective mother’s age, egg reserve, and health status.

Success Rate of Pregnancy at Advanced Age

• In women under 35: Pregnancy rate ≈ 45%
• Between the ages of 38–40: Pregnancy rate ≈ 25%
• Ages 40 and over: Pregnancy rate ≈ 5–10%

These rates can vary depending on individual health status, egg quality, and the treatment method used. At FertiJin IVF Center, success rates are increased by applying special IVF protocols for older prospective mothers.

Conclusion

For women planning a pregnancy at an older age, it is crucial to consult a specialized IVF center without delay.
FertiJin Women’s Health and IVF Center increase success rates in advanced maternal age pregnancies with its expert medical staff and laboratory equipment.

👉 Book your appointment now

Frequently Asked Questions

Is it possible to get pregnant at 40?

Yes, it is possible. However, the success rate of natural pregnancy is low. With IVF treatment, the chance of success can reach up to 40%.

Is genetic testing necessary for pregnancy at an advanced age?

Yes, PGT genetic screening test is recommended, especially for expectant mothers over the age of 38.

Is there an age limit for IVF treatment?

Legally, it is possible up to the age of 50, but the success rate decreases after the age of 43.