What is Microinjection (ICSI)?
Microinjection (ICSI) is an advanced laboratory method applied to increase fertilization in in vitro fertilization (IVF) treatments.
In this method, a single healthy sperm is injected into a mature egg cell with the help of microscopic devices.
The aim is to increase the probability of the sperm fertilizing the egg and to obtain a healthy embryo.
📍 FertiJin Women’s Health and IVF Center – Şişli, Istanbul achieves high success rates with the microinjection (ICSI) method.
👉 Make an appointment now for a free preliminary consultation
How is Microinjection (ICSI) Performed?
The ICSI procedure is carried out under laboratory conditions using a micromanipulator device.
The stages are as follows:
- Egg Retrieval (OPU): The eggs taken from the woman are examined in the laboratory.
- Sperm Preparation: The sperm sample taken from the man is processed through special procedures and the highest quality sperm are selected.
- Microinjection Procedure: One sperm is injected into each mature egg with a microscopic needle.
- Embryo Development: The fertilized eggs are developed in special solutions inside incubator devices that mimic the uterus.
- Evaluation: After 16–18 hours, it is observed whether fertilization has successfully occurred.
During this process, the quality and development of the embryos are closely monitored.
In Which Situations is Microinjection (ICSI) Applied?
The ICSI method is especially preferred in cases of male factor infertility.
However, it can also be applied in some female-related problems.
👨 Male-related conditions:
- Low sperm count (oligozoospermia)
- Poor sperm motility (asthenozoospermia)
- Sperm morphology disorders (teratozoospermia)
- Obtaining sperm by surgical methods in cases of azoospermia (TESE, PESA, etc.)
- Previous fertilization failure in classical IVF treatment
👩 Female-related conditions:
- Low number of mature eggs
- IVF attempts with low fertilization rates
💡 FertiJin IVF Center increases success rates by planning the microinjection procedure according to individual patient characteristics.
Advantages of the Microinjection (ICSI) Method
ICSI has many advantages compared to the classical IVF method:
- ✅ The fertilization rate is higher than IVF.
- ✅ Fertilization can be achieved even with low sperm count.
- ✅ It increases the chance of pregnancy in couples with sperm morphology or motility problems.
- ✅ It can be applied together with surgical sperm retrieval methods in conditions such as azoospermia.
- ✅ The risk of miscarriage decreases thanks to healthy embryo selection.
What Does the Success Rate of Microinjection (ICSI) Depend On?
The success of microinjection depends on several main factors:
| Success Factor | Explanation |
|---|---|
| Egg Quality | Mature and high-quality eggs support embryo development. |
| Sperm Quality | Healthy and motile sperm increase the chance of fertilization. |
| Embryo Development | Not every embryo may have the same quality. Monitoring is very important. |
| Maternal Age | The success rate is higher at younger ages. |
🔹 At FertiJin, the success rate in ICSI procedures is quite high thanks to appropriate patient selection and advanced laboratory conditions.
Microinjection (ICSI) Prices
The price of microinjection treatment;
- The laboratory technology used,
- The patient’s clinical condition,
- The doctor’s field of expertise
may vary depending on these factors.
💬 Please click for current price information and personal evaluation.
Frequently Asked Questions
What is the difference between Microinjection (ICSI) and IVF?
In IVF, sperm and egg are placed in the same environment and fertilization is expected.
In ICSI, sperm is directly injected into the egg. In this way, the chance of fertilization increases.
Is the microinjection procedure painful?
No. The laboratory part of the procedure is performed completely outside the body. Egg retrieval from the woman is performed painlessly under short-term anesthesia.
Who is microinjection suitable for?
It is suitable for couples with low sperm count, low sperm motility, or those who have experienced previous IVF failure.
What is the pregnancy rate after microinjection?
When appropriate patient selection is made, the fertilization rate can reach 70–90%, and the pregnancy rate can reach up to 50%.